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Ion Channels >> Intracellular Ion Channels >> Ryanodine Receptor Channels >> Antibodies

Anti-Ryanodine Receptor 2

Cardiac Ryanodine Receptor, RyR2
  • Antigen included
    Antigen included
  • Shipped at room temp.
    Shipped at room temp.
  • QC tested
    QC tested
  • Cat #: ARR-002
  • Size: 25 µl, 50 µl, 0.2 ml
  • Source: Rabbit
  • Type:  Polyclonal
Application: IC, IH, WB
Reactivity: H, M, R
May also work in: IFC, IP
Application key: CBE- Cell-based ELISA, FC- Flow cytometry, IC- Immunocytochemistry,
IE- Indirect ELISA, IFC- Indirect flow cytometry, IH- Immunohistochemistry, IP- Immunoprecipitation,
LCI- Live cell imaging, N- Neutralization, WB- Western blot     
Species reactivity key: H- Human, M- Mouse, R- Rat
Control antigen included Lyophilized powder
General information
Alomone Labs is pleased to offer a highly specific antibody directed against an epitope of human Ryanodine receptor 2 (RyR2). Anti-Ryanodine Receptor 2 antibody (#ARR-002) can be used in western blot, immunocytochemistry and immunohistochemistry applications. It has been designed to recognize RyR2 from human, rat and mouse samples.

Related products for control experiments:
Control peptide antigen (supplied with the antibody free of charge).

Anti-Ryanodine Receptor 2 antibody (#ARR-002) in the literature:
Western blot analysis (WB):
- Rat intrapulmonary artery lysate (1:400) (see Dahan, D. et al. (2012) in Product Citations).

Immunohistochemistry (IH):
- Rat heart sections (1:50) (see Zhu-Mauldin, X. et al. (2012) in Product Citations).
- Rat tibialis anterior muscle sections (1:100) (see Kraner, S.D. et al. (2011) in Product Citations).

Immunocytochemistry (IC):
- Mouse primary hippocampal neurons (1:300) (see Gan, K.J. et al. (2015) in Product Citations).

If you know of a relevant citation for this product please let us know.
Scientific Background
Product Citation
Western blot
Anti-Ryanodine_Receptor_2 - Western blot analysis of rat heart membranes:
Western blot analysis of rat heart membranes:
1. Anti-Ryanodine Receptor 2 antibody (#ARR-002), (1:200).
2. Anti-Ryanodine Receptor 2 antibody, preincubated with the control peptide antigen.
Anti-Ryanodine_Receptor_2 - Expression of Ryanodine Receptor 2  in rat cardiac muscle
Expression of Ryanodine Receptor 2  in rat cardiac muscle
Immunohistochemical staining of paraffin-embedded sections of rat myocardium using Anti-Ryanodine Receptor 2 antibody (#ARR-002), (1:50). Staining is specific for cardiomyocytes while smooth muscles cells in the artery walls are negative (red arrows). Hematoxilin is used as the counterstain.
Anti-Ryanodine_Receptor_2 - Expression of Ryanodine Receptor 2 in mouse cerebellum
Expression of Ryanodine Receptor 2 in mouse cerebellum
 Immunohistochemical staining of mouse cerebellum frozen sections with Anti-Ryanodine Receptor 2 antibody (#ARR-002), (1:100), (green fluorescence). A. The highest expression of Ryanodine Receptor 2 is in the molecular layer (Asterisk) but there is also some expression in the soma of Purkinje cells (arrows). B. In the same section, there is staining for parvalbumin (red), a marker for Purkinje cells. C. Merged image of panels A and B demonstrates that Ryanodine Receptor 2 is localized both in the area surrounding the dendritic tree and in the soma of Purkinje cells. DAPI is used as the counterstain (blue).
Mouse primary hippocampal neurons (1:300) (see Gan, K.J. and Silverman, M.A. (2015) Mol. Biol. Cell 26, 1058.)
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For research purposes only, not for human use
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