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Kir Channel Blocker Explorer Kit 

A Screening Package of Kir Channel Blockers Economically Priced
  • Bioassay tested
    Bioassay tested
  • Shipped at room temp.
    Shipped at room temp.
  • Cat #: EK-112
  • Size: 9 vials
General information
Kir1.1 (ROMK1) was the first member of the family of inward rectifying Kchannels to be cloned1. The family includes 15 members that are structurally and functionally different from the voltage-dependent K+ channels.

The family’s topology consists of two transmembrane domains that flank a single and highly conserved pore region with intracellular N- and C-termini. As is the case for the voltage-dependent K+ channels the functional unit for the Kir channels is composed of four subunits that can assembly as either homo or heterotetramers.

Kir channels are characterized by a K+ efflux that is limited by depolarizing membrane potentials thus making them essential for controlling resting membrane potential and K+ homeostasis2.

Alomone Labs is pleased to offer the Kir Channel Blocker Explorer Kit (#EK-112). The Explorer Kit contains many classical Kir channel blockers, ideal for screening purposes.

Carvedilol     #C-180     1 x 50 mg
δ-Dendrotoxin     #D-380     1 x 70 µg
Lq2     #RTL-550     1 x 5 µg
Rosiglitazone     #R-125     1 x 10 mg
Tertiapin     #STT-250     1 x 0.1 mg
Tertiapin-LQ     #STT-220     1 x 0.5 mg
Tertiapin-Q     #STT-170     1 x 0.1 mg
VU590 dihydrochloride     #V-130     1 x 5 mg
VU591 hydrochloride     #V-126     1 x 5 mg

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For research purposes only, not for human use
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