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Other >> Kits & Packs >> Explorer Kits >> Antibody Explorer Kits

Two-Pore Domain K+ Channel Antibody Explorer Kit

A Screening Package of Two-Pore Domain K+ Channel Antibodies Economically Priced
  • Antigen included
    Antigen included
  • Shipped at room temp.
    Shipped at room temp.
  • QC tested
    QC tested
  • Cat #: AK-202
  • Size: 26 vials
Application key: CBE- Cell-based ELISA, FC- Flow cytometry, IC- Immunocytochemistry,
IE- Indirect ELISA, IFC- Indirect flow cytometry, IH- Immunohistochemistry, IP- Immunoprecipitation,
LCI- Live cell imaging, N- Neutralization, WB- Western blot     
Species reactivity key: H- Human, M- Mouse, R- Rat
Control antigen included Lyophilized powder
General information
Two pore domain K+ channel (K2P) family consists of 15 members which are further divided to six subfamilies on the basis of structural and functional properties. All family members are tightly controlled by various chemical and physical stimuli such as pH, oxygen tension, lipids, mechanical stretch, G-protein coupled receptors, transmitters and other endogenous modulators, and are targets for clinically important compounds such as volatile anesthetic. These channels are also known as "leak channels". This name is given since they are open across the physiological voltage range, show little voltage or time dependence and are believed to underlie many of the K+ leak currents. This leak is active during the rest period of excitable cells, stabilizes membrane potential below firing threshold and hasten repolarization in many neurons including cerebellar granular neurons.

Alomone Labs is pleased to offer the Two-Pore Domain K+ Channel Antibody Explorer Kit (#AK-202). This Explorer Kit includes antibodies targeted against K2P channels along with their respective peptide control antigen. An ideal tool for screening purposes.

Anti-K2P1.1 (TWIK-1) (extracellular)     #APC-110     1 x 50 µl
Anti-K2P2.1 (TREK-1)     #APC-047     1 x 50 µl
Anti-K2P2.1 (TREK-1)     #AGP-049     1 x 50 µl
Anti-K2P3.1 (TASK-1)     #APC-024     1 x 50 µl
Anti-K2P4.1 (TRAAK)     #APC-108     1 x 50 µl
Anti-K2P5.1 (TASK-2)     #APC-037     1 x 50 µl
Anti-K2P6.1 (TWIK-2)     #APC-040     1 x 50 µl
Anti-K2P9.1 (TASK-3) (extracellular)     #APC-044     1 x 50 µl
Anti-K2P10.1 (TREK-2)     #APC-055     1 x 50 µl
Anti-K2P12.1 (THIK-2) (extracellular)     #APC-169     1 x 50 µl
Anti-K2P13.1 (THIK-1) (extracellular)     #APC-121     1 x 50 µl
Anti-K2P15.1 (TASK5) (extracellular)     #APC-158    1 x 50 µl
Anti-K2P18.1 (TRESK) (extracellular)     #APC-122     1 x 50 µl

Each antibody is supplied with its respective control peptide antigen.
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Price (USD):
For research purposes only, not for human use
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