Antagonists

5-Hydroxytryptamine Receptors (Serotonin Receptors)

Antagonists

Serotonin (5-hydroxytryptamine, 5-HT) plays unequivocally a most important role in the normal physiology amongst higher eukaryotes, as do most neurotransmitters. To date, some fifteen serotonin receptors have been cloned and grouped into seven families (5-HT1-5-HT7) based on their signaling mechanisms. The 5-HT1 receptor class comprises 5 different receptors with ranging homology. Apart from 5-HT3, all serotonin receptors belong to the G-Protein Coupled Receptor superfamily and therefore span the membrane seven times.

Displaying 1 to 3 products (out of 3 products)
  • Amitriptyline hydrochloride

    A Blocker of L-Type CaV Channels, an Antagonist of 5-HT2 Serotonin Receptors, and an Agonist of α-Adrenoceptors

    Cat # A-155
    Source Synthetic
    MW 313.86
    Target L-type Ca2+ channels, α-adrenergic receptors, 5-HT2 serotonin receptors
    • Lyophilized Powder
  • Mirtazapine

    An Antagonist of 5-HT2, 5-HT3, Histamine H1 Receptors and α2-Adrenoceptor

    Cat # M-130
    Source Synthetic
    MW 265.4
    Target 5-HT3, 5-HT2, Histamine H1, α2 adrenergic receptors
    • Lyophilized Powder
  • SDZ 205-557 hydrochloride

    An Antagonist of 5-HT3 Channels and 5-HT4 Receptors

    Cat # S-145
    Source Synthetic
    MW 337.2
    Target 5-HT3, 5HT4 receptors
    • Lyophilized Powder

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Displaying 1 to 3 products (out of 3 products)