Antagonists

Dopamine Receptors

Antagonists

DA receptors belong to the G-protein coupled receptors superfamily, and are prominent in the vertebrate central nervous system (CNS) as well as the peripheral nervous system (PNS). The neurotransmitter dopamine, a precursor of noradrenaline and adrenaline, is one of the main endogenous catecholamine ligand for DA receptors. There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5, based on their sequence homology, pharmacology and functional properties. Several neuropsychiatric disorders are derived from abnormal dopamine receptor signaling and dopaminergic nerve dysfunction.

Displaying 1 to 3 products (out of 3 products)
  • Chlorpromazine hydrochloride

    An Antagonist of nAChRs and an Antagonist of Dopamine Receptors

    Cat # C-165
    Source Synthetic
    MW 355.32
    Target nAChR, Dopamine receptors
  • Penfluridol

    A T-Type Ca2+ Channel Blocker and D2 Receptor Antagonist

    Cat # P-135
    Source Synthetic
    MW 523.96
    Target T-type Ca2+ channels, D2 receptor
  • Trifluoperazine dihydrochloride

    A Blocker of KV4.3 channel and an Inhibitor of D1 and D2 Dopamine Receptors

    Cat # T-175
    Source Synthetic
    MW 480.4
    Target KV4.3 channels, D1, D2 dopamine receptors

* See product page

Displaying 1 to 3 products (out of 3 products)