Antagonists

GABA(A) Receptors

Antagonists

GABA(A) Receptors are ionototropic γ-aminobutyric acid type A receptors. Most of the fast inhibitory synaptic transmissions in the brain are mediated by these ligand-gated ion channels in response in to γ-aminobutyric binding.
To date 19 GABA(A) Receptors have been cloned in the mammalian central nervous system (CNS) and are classified by their sequence identity into 7 different subunits (α, β, γ, δ, ε, π, and θ). They consist of pentameric structures assembled by different subunits which are mainly permeable to Cl that act to reduce neuronal excitation.

Displaying 1 to 20 (out of 26 products)
  • α-Asarone

    An Antagonist of NaV Channels, GABA(A) Receptors and an Inhibitor of TrkB Receptor

    Cat # A-260
    Source Natural
    MW 208.3
    Target NaV channels, GABA(A) receptors, TrkB receptors
  • α-Bungarotoxin

    A Potent Antagonist of α7 and Muscle nAChR and GABA(A) Receptor Subtypes

    Cat # B-100
    Source Natural peptide
    MW 7984 Da.
    Target α7, α1/β1/γ/δ nAChR, GABA(A) receptor subtypes
  • α-Bungarotoxin-ATTO-488

    A Fluorescent Conjugate for Sensitive Detection of Neuromuscular Junctions, GABA(A) Receptors, nAChRs, and α-Bungarotoxin Binding Sites

    Cat # B-100-AG
    Source Modified natural protein
    MW ~9140 Da.
    Target α7, α1/β1/γ/δ nAChR and GABA(A) receptor subtypes
  • α-Bungarotoxin-ATTO-633

    A Fluorescent Conjugate for Sensitive Detection of Neuromuscular Junctions, GABA(A) Receptors, nAChRs, and α-Bungarotoxin Binding Sites

    Cat # B-100-FR
    Source Modified natural protein
    MW ~9140 Da.
    Target α7, α1/β1/γ/δ nAChR and GABA(A) receptor subtypes
  • α-Bungarotoxin-Biotin

    A Biotinylated Conjugate for Sensitive Detection of Neuromuscular Junctions, GABA(A) Receptors, nAChRs, and α-Bungarotoxin Binding Sites

    Cat # B-100-B
    Source Modified natural protein
    MW ~9030 Da.
    Target α7, α1/β1/γ/δ nAChR, GABA(A) receptor subtypes
  • α-Bungarotoxin-FITC

    A Fluorescent Conjugate for Sensitive Detection of Neuromuscular Junctions, GABA(A) Receptors, nAChRs, and α-Bungarotoxin Binding Sites

    Cat # B-100-F
    Source Modified natural protein
    MW ~8406 Da.
    Target α7, α1/β1/γ/δ nAChR and GABA(A) receptor subtypes
  • Amentoflavone

    A Negative Allosteric Modulator of GABA(A) Receptors

    Cat # A-165
    Source Natural
    MW 538.46
    Target GABA(A) receptors
  • (+)-Bicuculline

    A Potent Antagonist of GABA(A) Receptor Channels

    Cat # B-135
    Source Synthetic
    MW 367.4
    Target GABA(A) receptors
  • (-)-Bicuculline methiodide

    An Antagonist of GABA(A) Receptors

    Cat # B-136
    Source Synthetic
    MW 509.27
    Target GABA(A) receptors
  • (-)-Bicuculline methochloride

    An Antagonist of GABA(A) Receptors

    Cat # B-137
    Source Synthetic
    MW 417.84
    Target GABA(A) receptors
  • Bilobalide

    An Antagonist of 5-HT3A and GABA(A) Receptors

    Cat # B-145
    Source Natural
    MW 326.3
    Target 5-HT3A, GABA(A) receptors
  • Etbicyphat

    An Antagonist of GABA(A) Receptors

    Cat # E-175
    Source Synthetic
    MW 178.12
    Target GABA(A) receptors
  • Flumazenil

    An Antagonist of GABA(A) Receptors

    Cat # F-145
    Source Synthetic
    MW 303.3
    Target GABA(A) receptors
  • GABA(A)-compound 1b

    A Novel Antagonist of GABA(A) Receptors

    Cat # CMG-004
    Source Synthetic
    MW 415.39
    Target GABA(A) receptors
  • Gabazine

    An Antagonist of GABA(A) and Glycine Receptors

    Cat # G-215
    Source Synthetic
    MW 287.32
    Target GABA(A), Glycine receptors
  • Gabazine hydrobromide

    An Antagonist of GABA(A) and Glycine Receptors

    Cat # G-216
    Source Synthetic
    MW 368.23
    Target GABA(A), Glycine receptors
  • MmTX1

    A Super Potent Allosteric Modulator of GABA(A) Receptors

    Cat # STM-550
    Source Synthetic peptide
    MW 7205 Da.
    Target GABA(A) receptors
  • Oroxylin A

    An Antagonist of GABA(A) Receptors

    Cat # O-160
    Source Natural
    MW 284.26
    Target GABA(A) receptors
  • Picrotoxin

    An Antagonist of GABA(A), Glycine, and 5-HT3 Receptors

    Cat # P-325
    Source Natural
    MW 602.58
    Target GABA(A), Glycine, 5-HT3 receptors
  • Tracazolate hydrochloride

    A Modulator of GABA(A) Receptors

    Cat # T-230
    Source Synthetic
    MW 340.85
    Target GABA(A) receptors

* See product page

Displaying 1 to 20 (out of 26 products)