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Antagonists

Nicotinic Acetylcholine Receptors

Antagonists

nAChRs are pentameric complexes made up of combinations of a number of different nAChR subunits, which can be classified as α subunits, containing two cysteine residues at positions analogous to Cys192 and Cys193, and non-alpha subunits (‘structural’ subunits), which can be defined as β subunits when they are expressed in the vertebrate nervous system. There are nine α subunits (α2–α10) and three β subunits (β2, β3, and β4) in the CNS. Nicotinic receptors are assembled as combinations of α (2-6) and and β (2-4) subunits.

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Displaying 1 to 20 (out of 38 products)

  • α-Bungarotoxin

    A Potent Antagonist of α7 and Muscle nAChR and GABA(A) Receptor Subtypes

    Cat # B-100
    MW 7984 Da.
    Target α7, α1/β1/γ/δ nAChR, GABA(A) receptor subtypes
    More info
    • Lyophilized Powder

  • α-Bungarotoxin-ATTO-488

    A Fluorescent Conjugate for Sensitive Detection of Neuromuscular Junctions, GABA(A) Receptors, nAChRs, and α-Bungarotoxin Binding Sites

    Cat # B-100-AG
    MW ~9140 Da.
    Target α7, α1/β1/γ/δ nAChR and GABA(A) receptor subtypes
    More info
    • Lyophilized Powder

  • α-Bungarotoxin-ATTO-633

    A Fluorescent Conjugate for Sensitive Detection of Neuromuscular Junctions, GABA(A) Receptors, nAChRs, and α-Bungarotoxin Binding Sites

    Cat # B-100-FR
    MW ~9140 Da.
    Target α7, α1/β1/γ/δ nAChR and GABA(A) receptor subtypes
    More info
    • Lyophilized Powder

  • α-Bungarotoxin-Biotin

    A Biotinylated Conjugate for Sensitive Detection of Neuromuscular Junctions, GABA(A) Receptors, nAChRs, and α-Bungarotoxin Binding Sites

    Cat # B-100-B
    MW ~9030 Da.
    Target α7, α1/β1/γ/δ nAChR, GABA(A) receptor subtypes
    More info
    • Lyophilized Powder

  • α-Bungarotoxin-FITC

    A Fluorescent Conjugate for Sensitive Detection of Neuromuscular Junctions, GABA(A) Receptors, nAChRs, and α-Bungarotoxin Binding Sites

    Cat # B-100-F
    MW ~8406 Da.
    Target α7, α1/β1/γ/δ nAChR and GABA(A) receptor subtypes
    More info
    • Lyophilized Powder

  • α-Conotoxin AuIA

    An Antagonist of α3/β4 nAChR

    Cat # STC-960
    MW 1726 Da.
    Target α3/β4 nAChR
    More info
    • Lyophilized Powder

  • α-Conotoxin AuIB

    A Potent Antagonist of Mammalian α3/β4 Neuronal nAChR

    Cat # STC-310
    MW 1572 Da.
    Target α3/β4 nAChR
    More info
    • Lyophilized Powder

  • α-Conotoxin EI

    An Antagonist of α1/β1/γ/δ nAChR

    Cat # STC-900
    MW 2094 Da.
    Target α1/β1/γ/δ nAChR
    More info
    • Lyophilized Powder

  • α-Conotoxin EIIB

    A Potent Antagonist of α1/β1/δ/γ nAChR

    Cat # STC-230
    MW 1754.5 Da.
    Target Muscle nAChR
    More info
    • Lyophilized Powder

  • α-Conotoxin GI

    A Potent Antagonist of α1/β1/δ/γ nAChR

    Cat # STC-500
    MW 1438 Da.
    Target α1/β1/δ/γ nAChR
    More info
    • Lyophilized Powder

  • α-Conotoxin ImI

    A Potent Antagonist of Mammalian α3/β2 Neuronal nAChR

    Cat # C-290
    MW 1351 Da.
    Target α3/β2 nAChR
    More info
    • Lyophilized Powder

  • α-Conotoxin ImI-ATTO-590

    A Potent Antagonist of Mammalian α3/β2 nAChR Conjugated to the Fluorescent Dye ATTO-590

    Cat # C-290-AR
    MW 1924 Da.
    Target α3/β2 nAChR
    More info
    • Lyophilized Powder

  • α-Conotoxin LtIA

    A Novel Antagonist of α3/β2 nAChR

    Cat # STC-550
    MW 1601.8 Da.
    Target α3/β2 nAChR
    More info
    • Lyophilized Powder

  • α-Conotoxin MI

    A Potent Antagonist of Muscle α1/β1/γ/δ nAChR

    Cat # STC-370
    MW 1494 Da.
    Target α1/β1/γ/δ nAChR
    More info
    • Lyophilized Powder

  • α-Conotoxin MrIC

    An Antagonist and Partial Agonist of α7 nAChR

    Cat # STC-320
    MW 1839.09 Da.
    Target α7 nAChR
    More info
    • Lyophilized Powder

  • α-Conotoxin PeIA

    An Antagonist of nAChR and N-Type Ca2+ Channels

    Cat # STC-970
    MW 1652 Da.
    Target nAChR, CaV2.2 Ca2+ channels
    More info
    • Lyophilized Powder

  • α-Conotoxin PIA

    A Selective nAChRα6 Antagonist

    Cat # STC-870
    MW 1981 Da.
    Target α6 nAChR
    More info
    • Lyophilized Powder

  • α-Conotoxin SI

    A Potent Antagonist of Muscular α1/β1/δ/γ nAChR

    Cat # STC-825
    MW 1354 Da.
    Target Muscle nAChR
    More info
    • Lyophilized Powder

  • αA-Conotoxin OIVA

    An Antagonist of α1/β1/γ/δ (fetal muscle) nAChR

    Cat # STC-520
    MW 1848 Da.
    Target α1/β1/γ/δ nAChR
    More info
    • Lyophilized Powder

  • αA-Conotoxin PIVA

    A Potent Antagonist of Muscle Fetal α1/β1/γ/δ nAChR

    Cat # STC-600
    MW 2651 Da.
    Target α1/β1/γ/δ nAChR
    More info
    • Lyophilized Powder

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Displaying 1 to 20 (out of 38 products)
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