Immuno-Colocalization Products

Alomone Labs has developed two innovative platforms for studying protein-protein interaction and/or protein co-localization in complex immunostaining or immunoprecipitation protocols:

 

ATTO-Conjugated Antibodies: These antibodies can be used in immunohistochemistry (IHC) and immunocytochemistry (ICC) with same species antibodies.

 

Save time and resources with ONE antibody.

 

Benefits of immunostaining with ATTO-conjugated antibodies:
Direct immuno-fluorescence
Secondary antibodies are not necessary
Ideal for immuno-colocalization with same species/host antibodies

 

More on ATTO dyes

 

Guinea Pig-Raised Antibodies: Antibodies raised in guinea pig can be used with any non-guinea pig second species antibodies (e.g. antibodies raised in mouse, rabbit, goat, etc.) in complex immunostaining or immunoprecipitation protocols. Our line of guinea pig raised antibodies can be combined with any of our rabbit-raised or ATTO-conjugated antibodies in complex immunostaining protocols.

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Antibodies to Interacting Proteins

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

Antibodies to Interacting Proteins

The cystic fibrosis transmembrane conductance regulator (CFTR) is the most dominant Cl channel in several epithelial tissues, especially in lung and colon. Remarkably, CFTR is a member of the ATP-binding cassette (ABC) transporter superfamily that uses ATP hydrolyzation as the driving force for the translocation of a wide variety of substrates including sugars, amino acids, proteins and hydrophobic compounds, across cellular membranes. The CFTR is unique among ABC transporters in that it is a cAMP-regulated Cl channel. It shares the superfamily topology of 12 transmembrane domains with two nucleotide-binding domains (NBDs) and a regulatory (R) domain in the large third intracytoplasmic loop that is phosphorylated in multiple sites by PKA. Mutations in the CFTR gene cause channel dysfunction in several ways, ranging from complete loss of surface expression to diminished Cl secretion. Defects in the CFTR gene cause cystic fibrosis (CF), the most common genetic disease among Caucasians, as well as a form of male sterility.

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  • Anti-Calnexin-ATTO-594 Antibody

    A Rabbit Polyclonal Antibody to Calnexin Conjugated to the Fluorescent Dye ATTO-594

    Cat # ACS-009-AR
    Type Polyclonal
    Source Rabbit
    Applications ih, ic*
    Reactivity h, m, r
    • New
    • Lyophilized Powder
    • Antigen Incl.

* See product page

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