Guinea Pig-Raised Antibodies: Antibodies raised in guinea pig can be used with any non-guinea pig second species antibodies (e.g. antibodies raised in mouse, rabbit, goat, etc.) in complex immunostaining or immunoprecipitation protocols. Our line of guinea pig raised antibodies can be combined with any of our rabbit-raised or ATTO-conjugated antibodies in complex immunostaining protocols.
The metabolism of larachidonic acid gives rise to a family of molecules termed leukotrienes. Leukotrienes influence cellular/physiological processes by binding to leukotriene receptors, which belong to the superfamily of G-protein coupled receptors. Members include CysLT1, involved in bronchoconstriction. CysLT2, which plays a role in inflammation. BLT1, which mediates proinflammatory actions and BLT2, whose role remains to be deciphered. These receptors are involved in a plethora of pathologies such as asthma, inflammatory diseases (including rheumatoid arthritis) and more.