Blockers

Mechanosensitive Ion Channels

Blockers

Mechanosensitive ion channels (MS channels) represent a diverse population of ion channels. Other membrane-associated proteins with different biophysical properties apart from ion channels, specialized cytoskeletal proteins, cell junction molecules and G-protein-coupled receptors and kinases, among many others are also considered mechanosensitive. MS channels integrate a variety of mechanical stimuli such as shear stress, tension, torsion, and compression and translate them into short-term effects (i.e., changes in ion concentrations and voltage) and long-term effects via changes in gene expression.

Displaying 1 to 19 products (out of 19 products)
  • A 967079

    A Blocker of TRPA1 Channels

    Cat # A-225
    Source Synthetic
    MW 207.2
    Target TRPA1 channels
  • Amiloride hydrochloride

    Blocker of ENaC/ASIC/Degenerin Channels

    Cat # A-140
    Source Synthetic
    MW 266.09
    Target ENaC, ASIC, TRPP3 channels, NHE-1 transporter
  • AP-18

    A Reversible TRPA1 Channel Blocker

    Cat # A-250
    Source Synthetic
    MW 209.7
    Target TRPA1 channels
  • APETx2

    A Blocker of ASIC3 Channel

    Cat # STA-160
    Source Synthetic
    MW 4561 Da.
    Target ASIC3 channels
  • Chembridge-5861528

    A Selective Blocker of TRPA1 Channel

    Cat # C-235
    Source Synthetic
    MW 369.4
    Target TRPA1 channels
  • DMA

    A Blocker of TRPA1 Channel and Selective Blocker of Na+/H+ Antiporters

    Cat # D-165
    Source Synthetic
    MW 294.1
    Target TRPA1 channel and Na+/H+ exchangers
  • GsMTx-4

    A Blocker of NaV1.7 Channels, TRPC1, TRPC6 and Piezo1 Channels

    Cat # STG-100
    Source Synthetic peptide
    MW 4096 Da.
    Target NaV1.7 channels, TRPC1, TRPC6
  • HC-030031

    A Selective TRPA1 Channel Blocker

    Cat # H-105
    Source Synthetic
    MW 355.4
    Target TRPA1 channels
  • LASSBio-1135

    A Blocker of TRPV1 Channels and Antagonist of TNF-α Receptors

    Cat # L-190
    Source Synthetic
    MW 286.3
    Target TRPV1 channels, TNF-α receptors
  • Linopirdine

    A Blocker of KCNQ (KV7) Channels

    Cat # L-155
    Source Synthetic
    MW 391.46
    Target KCNQ K+ channels
  • Linopirdine dihydrochloride

    A Blocker of KCNQ (KV7) Channels

    Cat # L-156
    Source Synthetic
    MW 464.39
    Target KCNQ K+ channels
  • Mambalgin-3

    A Blocker of ASIC1a and ASIC1b Channels

    Cat # M-300
    Source Natural protein
    MW 6566 Da.
    Target ASIC1 channels
  • Psalmotoxin-1

    A Potent Blocker of ASIC1a Channels

    Cat # STP-200
    Source Synthetic peptide
    MW 4689.5 Da.
    Target ASIC1a channels
  • ProTx-I

    A Blocker of NaV, CaV3.1, KV2.1 and TRPA1 Channels

    Cat # STP-400
    Source Synthetic peptide
    MW 3988 Da.
    Target NaV, CaV3.1, KV2.1, TRPA1 channels
  • XE991

    A Blocker of KCNQ Channels

    Cat # X-100
    Source Synthetic
    MW 376.45
    Target KCNQ K+ channels
  • XE991 dihydrochloride

    A Blocker of KCNQ Channels

    Cat # X-101
    Source Synthetic
    MW 449.37
    Target KCNQ K+ channels
  • TRPA1 Channel Blocker Explorer Kit

    A Screening Package of TRPA1 Channel Blockers Economically Priced

    Cat # EK-121
    • Lyophilized Powder
    • Bioassay Tested
    • Shipped at Room Temp.
    • 100% Net Peptide
  • TRPA1 Channel Modulator Explorer Kit

    A Screening Package of TRPA1 Channel Modulators Economically Priced

    Cat # EK-120
    • Lyophilized Powder
    • Bioassay Tested
    • Shipped at Room Temp.
    • 100% Net Peptide
  • TRPA1 Channel Basic Research Pack

    All You Need for TRPA1 Channel Research

    Cat # ESB-302
    • Lyophilized Powder
    • Antigen Incl.
    • Bioassay Tested
    • Shipped at Room Temp.

* See product page

Displaying 1 to 19 products (out of 19 products)