Extracellular antibodies are ideal research tools for cell-surface proteins.
No permeabilization/fixation because using extracellular antibodies allows you to work with live cells!
Benefits of live cell imaging:
✓ Monitor cell movement
✓ Study protein transport across the cell
✓ Investigate protein internalization
Mitochondrial Ion Channels
Mitochondria are the main energy producing organelles of the cell. They are comprised of an outer membrane (OMM), an inner membrane (IMM), a space between them and a matrix enclosed within the IMM. Many of the ion channels found in mitochondria are vital for energy supply by the mitochondria for the rest of the cell. Channels are located both in the OMM and IMM.