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Glucagon-like peptides 1 and 2 are two peptides secreted following food consumption. They exert their effect via glucagon-like peptide 1 receptor and glucagon-like peptide 2 receptor respectively. The expression of the formeer receptor is more limited than that of glucagon-like peptide 2 receptor. The glucagon-like peptide 1 system may serve as a target for the treatment of diabetes.