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Antibodies raised in guinea pig can be used with antibodies raised in mouse, rabbit, goat, etc. in complex immunostaining or immunoprecipitation protocols.

K⁺ channels are tetrameric integral membrane proteins that form aqueous pores through which K⁺ can flow, and are found in many organisms. In neurons, K⁺ channels are involved in maintaining the resting potential, repolarizing the membrane after action potentials, and controlling the timing of repetitive firing.