Alomone Labs has developed two innovative platforms for studying protein-protein interaction and/or protein co-localization in complex immunostaining or immunoprecipitation protocols:
ATTO-Conjugated Antibodies: These antibodies can be used in immunohistochemistry (IHC) and immunocytochemistry (ICC) with same species antibodies.
Save time and resources with ONE antibody.
Benefits of immunostaining with ATTO-conjugated antibodies:
✓ Direct immuno-fluorescence
✓ Secondary antibodies are not necessary
✓ Ideal for immuno-colocalization with same species/host antibodies
Guinea Pig-Raised Antibodies: Antibodies raised in guinea pig can be used with any non-guinea pig second species antibodies (e.g. antibodies raised in mouse, rabbit, goat, etc.) in complex immunostaining or immunoprecipitation protocols. Our line of guinea pig raised antibodies can be combined with any of our rabbit-raised or ATTO-conjugated antibodies in complex immunostaining protocols.
KCNQ genes encode members of the KV7 K+ channels. Structurally, the KCNQ family belongs to the six transmembrane domain category of K+ channels. Five members belong to this family (KCNQ1-KCNQ5) of which KCNQ2 to KCNQ5 are expressed in the nervous system. KCNQ5 is also expressed in visceral smooth muscle and skeletal muscle.
These channels form subunits of the low threshold voltage-gated K+ channel. KCNQ2 and KCNQ3 mostly form heteromers to form the M current. KCNQ5 is known to contribute to this current.