Nicotinic Acetylcholine Receptors

Biotinylated Toxins

Nicotinic Acetylcholine Receptors

nAChRs are pentameric complexes made up of combinations of a number of different nAChR subunits, which can be classified as α subunits, containing two cysteine residues at positions analogous to Cys192 and Cys193, and non-alpha subunits (‘structural’ subunits), which can be defined as β subunits when they are expressed in the vertebrate nervous system. There are nine α subunits (α2–α10) and three β subunits (β2, β3, and β4) in the CNS. Nicotinic receptors are assembled as combinations of α (2-6) and and β (2-4) subunits.

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  • α-Bungarotoxin-Biotin

    A Biotinylated Conjugate for Sensitive Detection of Neuromuscular Junctions, GABA(A) Receptors, nAChRs, and α-Bungarotoxin Binding Sites

    Cat # B-100-B
    Source Modified natural protein
    MW ~9030 Da.
    Target α7, α1/β1/γ/δ nAChR, GABA(A) receptor subtypes

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