K+ selective channels are some of the most widespread ion trafficking molecules in living organisms, with more than 70 genes encoding different K+ channels in humans. KV channels fall into one of the two classical categories of delayed rectifier (DR) and A-type. Delayed rectifier was the original name attributed to voltage-dependent K+ channels due to their delayed activation in squid giant axons. A-type channels are low voltage-activated, fast inactivating (therefore, transient) K+ channels. Specific KV toxins are often used to dissect the particular contribution of different subunits to native currents.
Alomone Labs is excited to offer a line of Overexpressed Membrane Fractions. These membrane fractions are Xenopus oocyte membrane lysates overexpressing a specific ion channel. Fractions are sold as a set of injected and non-injected oocytes and can be used as controls for Alomone Labs antibodies.
Overexpressed Membrane Fractions can also be purchased as a kit with their respective antibody. Membrane fractions enable end users to verify/validate the specificity of Alomone Labs antibodies.