Guinea Pig-Raised Antibodies: Antibodies raised in guinea pig can be used with any non-guinea pig second species antibodies (e.g. antibodies raised in mouse, rabbit, goat, etc.) in complex immunostaining or immunoprecipitation protocols. Our line of guinea pig raised antibodies can be combined with any of our rabbit-raised or ATTO-conjugated antibodies in complex immunostaining protocols.
Voltage-dependent Ca2+ channels (CaV) form an important route for Ca2+ entry into cells, upon deviations from the cells’ resting membrane potential. There are ten CaV α1 subunit genes, divided into three subfamilies on both a functional and sequence homology basis. The CaV1 subfamily includes four genes which encode the L-type channels, the CaV3 subfamily includes three genes encoding the T-type channels and the CaV2 subfamily consists of three isoforms encoding P/Q- , N- and R-type channels, with all three contributing to neurotransmitter release in neurons.