Alomone Labs has developed two innovative platforms for studying protein-protein interaction and/or protein co-localization in complex immunostaining or immunoprecipitation protocols:
ATTO-Conjugated Antibodies: These antibodies can be used in immunohistochemistry (IHC) and immunocytochemistry (ICC) with same species antibodies.
Save time and resources with ONE antibody.
Benefits of immunostaining with ATTO-conjugated antibodies:
✓ Direct immuno-fluorescence
✓ Secondary antibodies are not necessary
✓ Ideal for immuno-colocalization with same species/host antibodies
Guinea Pig-Raised Antibodies: Antibodies raised in guinea pig can be used with any non-guinea pig second species antibodies (e.g. antibodies raised in mouse, rabbit, goat, etc.) in complex immunostaining or immunoprecipitation protocols. Our line of guinea pig raised antibodies can be combined with any of our rabbit-raised or ATTO-conjugated antibodies in complex immunostaining protocols.
Vesicular monoamine transporters (VMAT) are transmembrane proteins located on membranes of monoaminergic neurons and are responsible for the uptake of cytosolic monoamines into synaptic vesicles. They store neurotransmitter molecules in synaptic vesicles for additional cycles of release. They are acidic glycoproteins encoded by the SLC18A1 gene and transport neurotransmitters including dopamine, serotonin, adrenaline, noradrenaline, histamine and norepinephrine. Its structure is composed of 12 transmembrane domains, the C and N-terminus are located in the cytosolic side of the vesicle. The glycosylation sites are located in the vesicular matrix on a loop between transmembrane domain I and II.