ASIC channels belong to the ENaC/Degenerin superfamily and are proton-gated ion channels which are not voltage-dependent. ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, ASIC4, and ASIC5. The topology of ASIC channels is predicted on the basis of that of ENaCs. However, different computational programs have depicted different structures for the channels.
Alomone Labs is excited to offer a line of Overexpressed Membrane Fractions. These membrane fractions are Xenopus oocyte membrane lysates overexpressing a specific ion channel. Fractions are sold as a set of injected and non-injected oocytes and can be used as controls for Alomone Labs antibodies.
Overexpressed Membrane Fractions can also be purchased as a kit with their respective antibody. Membrane fractions enable end users to verify/validate the specificity of Alomone Labs antibodies.