Inwardly rectifying K+ (Kir) channels have diverse physiological functions depending on their type and their location. To date, 15 Kir subunit genes have been identified and classified into seven subfamilies (Kir1 to Kir7). These subfamilies can be categorized into four functional groups: 1) classical Kir channels (Kir2.x), 2) G-protein gated Kir channels (Kir3.x), 3) ATP-sensitive K+ channels (Kir6.x), and 4) K+-transport channels (Kir1.x, Kir4.x, Kir5.x, and Kir7.x).
Alomone Labs is excited to offer a line of Overexpressed Membrane Fractions. These membrane fractions are Xenopus oocyte membrane lysates overexpressing a specific ion channel. Fractions are sold as a set of injected and non-injected oocytes and can be used as controls for Alomone Labs antibodies.
Overexpressed Membrane Fractions can also be purchased as a kit with their respective antibody. Membrane fractions enable end users to verify/validate the specificity of Alomone Labs antibodies.