Epithelial cells form a dynamic barrier that separates different physiological compartments. On one hand they provide a physical barrier that …
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Issue No. 19
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Contribution of Ion Channels in Pain Sensation
Many ion channels are located at the nociceptor peripheral terminal, affecting neuron excitability after injury and as a result affecting …
Continue readingVenom Peptides and their Mimetics as Potential Drugs
Venomous creatures have a sophisticated mechanism for prey capture which includes a vast array of biologically active compounds, such as …
Continue readingThe Role of p75NTR in Cancer
No generalizations about the role of this enigmatic receptor in cancer can be made. As in all other aspects of …
Continue readingKATP Channels: Linking Cell Metabolism to Cell Excitability
ATP-sensitive K+ channels (KATP channels) were described nearly 20 years ago in membrane patches of isolated ventricular myocytes. Since then, …
Continue readingInteractions of KCNE Auxiliary Subunits with KV and other Channels
KCNEs are integral membrane proteins that associate with and strongly modulate the activity of several ion channels. The different KCNE …
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