CNTF, a member of the cytokine family, was originally described as a neuronal survival factor in the chick cilia ganglia. …
Continue readingNeurotrophin Pathways
Issue No. 2
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pro-Neurotrophins: The Other Identity of Neurotrophins
The precursors of neurotrophins – pro-neurotrophins – have proven to be biologically active. This short report aims at pointing out …
Continue readingOff the Trk (with K252a)
The four mammalian neurotrophins (NTs) – NGF, BDNF, NT-3, and NT-4 – are renowned regulators of neural plasticity, function and …
Continue readingNT-3 and NT-4 at the Nerve Center of Neurotrophic Research
Neurotrophins have emerged more than 6 decades ago as the mysterious molecules behind neuronal well-being. Their wide range of activities …
Continue readingIn Focus: NGF Neutralization
Nerve growth factor (NGF), the founder of the neurotrophin superfamily, exerts a wide range of physiological functions not only in …
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