Alomone Labs is pleased to offer the α2-Adrenergic Receptor Antibody Explorer Kit (#AK-495). The Explorer Kit contains α2-adrenoceptor antibodies, ideal for screening purposes.
|Product Name||Cat #||Size|
|AAR-020||1 x 50 µl|
|AAR-021||1 x 50 µl|
|AAR-022||1 x 50 µl|
Adrenergic receptors (also called adrenoceptors) are the receptors for the catecholamines; adrenaline and noradrenaline (called epinephrine and norepinephrine in the United States). Adrenaline and noradrenaline play important roles in the control of blood pressure, myocardial contractile rate and force, airway reactivity, and a variety of metabolic and central nervous system functions.
Adrenoceptors are members of the G-protein coupled receptor (GPCR) superfamily of membrane proteins. They share a common structure of seven putative transmembrane domains, an extracellular N-terminus, and a cytoplasmic C- terminus. The adrenoceptors are divided into three types: α1, α2 and β-adrenoceptors. Each type is further divided into at least three subtypes: α1A, α1B, α1D, α2A, α2B, α2C, β1, β2, β31,2. The adrenoceptors are expressed in nearly all peripheral tissues and in the central nervous system1,2.