This product is freeze dried. All water molecules have been removed.
Every lot is tried & tested in a relevant biological assay.
Benishin, C.G. et al. (1988) Mol. Pharmacol. 34, 152.
Alomone Labs γ-Dendrotoxin inhibits cloned KV1.1 and KV1.2 channel currents heterologously expressed in Xenopus oocytes.KV1.1 (left, in 2 mM K+) and KV1.2 (right, in 5 mM K+) channels currents, elicited by 200 ms depolarization from holding potential of -100 mV to +20 mV, before and during application of 100 nM γ-Dendrotoxin (#D-370). 80% (n = 4) of the KV1.1 and 21% (n = 4) of the KV1.2 channels were inhibited by 100 nM γ-Dendrotoxin, respectively.
γ-Dendrotoxin is isolated from Dendroaspis angusticeps snake venom by modification of the procedures of Harvey1 and Benishin2 and purified to homogeneity.
γ-Dendrotoxin (#D-370) is a highly pure, natural, and biologically active peptide toxin.