- Abbott, J.R. and Litzinger M.J. (1994) Int. J. Devl. Neuroscience 12, 43.
- Alomone Labs ω-Conotoxin RVIA inhibits CaV2.2 channels expressed in Xenopus oocytes.A. Representative time course of ω-Conotoxin RVIA (#STC-850) inhibition of CaV2.2 maximum current. Membrane potential was held at -100 mV, current was elicited by a 100 ms voltage ramp to +60 mV every 10 sec, and was significantly inhibited by application of 0.5 µM ω-Conotoxin RVIA (top horizontal bar). B. Superimposed traces of CaV2.2 current after the application of control and 0.5 µM ω-Conotoxin RVIA (as indicated). Taken from experiment in A.
ω-Conotoxin RVIA is a 27 amino acid peptidyl toxin, originally isolated from the Conus radiatus (Rayed cone)1 venom and is a synthetic version of the peptide.
This peptide acts at presynaptic membranes by binding and blocking voltage-gated Ca2+ channels (CaV2.2)2.
ω-Conotoxin RVIA (#STC-850) is a highly pure, synthetic, and biologically active peptide toxin.