|Product Name||Cat #||Size|
Anti-Endothelin Receptor A Antibody
|AER-001||1 x 0.2 ml|
Anti-Endothelin Receptor B Antibody
|AER-002||1 x 0.2 ml|
|SPE-200||1 x 10 mg|
|SPE-160||1 x 1 mg|
|A-360||1 x 10 mg|
|A-350||1 x 10 mg|
|B-170||1 x 250 mg|
BQ-123 sodium salt
|B-185||1 x 10 mg|
BQ788 sodium salt
|B-176||1 x 5 mg|
|F-180||1 x 10 mg|
- Lyophilized Powder Lyophilized Powder
This product is freeze dried. All water molecules have been removed.
- Antigen Incl. Control Antigen Included
This antibody is shipped with its antigen FREE of charge!
Endothelin Receptor Basic Research Pack (#ESB-940) contains all you need for Endothelin Receptor research: Antibodies for each receptor and selective pharmacological tools, all in one budget friendly package!
The endothelin system is comprised of three active peptides, ET-1, 2, and 3, which are considered to be very powerful vasoconstrictive substances. In humans, endothelins mediate their actions via two specific G-Protein Coupled Receptors, ETAR and ETBR. Both ETAR and ETBR are present in heart and in human myocardium at similar levels1,2.
The endothelin receptors differ in their ligand specificity. While ETAR has varying affinities for the endothelin isoforms (ET-1 >ET-2>ET-3), ETBR shows no selective affinity.2,3 Subsequent studies have demonstrated the presence of endothelins in vascular as well as in non-vascular cells and tissues, having multiple biological activities.