This product is freeze dried. All water molecules have been removed.
The activity of this product has been verified and approved by our professional team.
Brueggemann, L.I. et al. (2012) Am. J. Physiol. 302, L120.
K+ channels (KCNQ/KV7) are expressed along myelinated and unmyelinated peripheral axons where their activation is expected to reduce axonal excitability1. Neurons express four KCNQ subunits that co-assemble to form either homo- or hetero-tetrameric voltage-gated channels2.
Flupirtine maleate is a centrally-acting, non-opioid analgesic with N-methyl-D-aspartate (NMDA) receptor antagonist property. Flupirtine maleate is an analgesic with muscle-relaxing properties that activates KCNQ channels. Flupirtine maleate is as effective as opioids to settle the pain in post-surgical cases, cancer related, neuropathic and myofascial in origin. The analgesic effect of flupirtine maleate does not appear to be associated with any central opioid effect3. The clinical use of flupirtine maleate is more appropriate as it lacks the typical side effects of the opioid drugs4.
Flupirtine Maleate (#F-150) is a highly pure, synthetic, and biologically active compound.
- Retigabine (#R-100)
- Anti-KCNQ2 Antibody (#APC-050)
- Anti-KCNQ3 Antibody (#APC-051)
- Anti-KCNQ1 Antibody (#APC-022)
- Anti-KCNQ5 Antibody (#APC-155)
- Anti-KCNE2 (MiRP1) Antibody (#APC-054)
- Anti-KCNE3 (MiRP2) Antibody (#APC-118)
- KCNQ (KV7) Channel Antibody Explorer Kit (#AK-221)
- hERG Related Channel Modulator Explorer Kit (#EK-109)
- Retigabine dihydrochloride (#R-101)
- SsTx Toxin (#STS-700)