Overview
Cat #:
Size:
1 g
Lot:
G150SM011
Alternative Name Glyburide, Glybenclamide, Micronase, Diabeta
Lyophilized Powder yes
Source Synthetic
MW: 494
Purity: >99%.
Form Lyophilized powder.
Effective concentration 1-100 µM.
Structure
Chemical name 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide.
Molecular formula C23H28ClN3O5S.
CAS No.: 10238-21-8
PubChem CID 3488
Activity 1-100 µM Glibenclamide activates human TRPA1 expressing cells1.
References-Activity
- Babes, A. et al. (2013) Eur. J. Pharmacol. 704, 15.
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility Up 200 mM in DMSO. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
- Alomone Labs Glibenclamide activates TRPA1 channels expressed in HEK-293 cells.Dose-response curve for the activation of human TRPA1 expressing HEK-293 cells loaded with Calcium 5 dye for changes in intracellular Ca2+ measurements. Calcium signal was apparent with 50 and 100 µM Glibenclamide (#G-150).
Target TRPA1, KATP channels
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
Citations