- Lyophilized Powder Lyophilized Powder
This product is freeze dried. All water molecules have been removed.
- Antigen Incl. Control Antigen Included
This antibody is shipped with its antigen FREE of charge!
Alomone Labs is pleased to offer the Glutamate Transporter Antibody Explorer Kit (#AK-440). The Explorer Kit contains glutamate transporter antibodies, ideal for screening purposes.
|Product Name||Cat #||Size|
Anti-EAAT1 (GLAST) (extracellular) Antibody
|AGC-021||1 x 50 µl|
Anti-EAAT2 (GLT-1) (extracellular) Antibody
|AGC-022||1 x 50 µl|
Anti-EAAT3 (EAAC1) Antibody
|AGC-023||1 x 50 µl|
Anti-EAAT4 (extracellular) Antibody
|AGC-024||1 x 50 µl|
Anti-SLC1A7 (extracellular) Antibody
|AGC-025||1 x 50 µl|
|AGC-035||1 x 50 µl|
|AGC-036||1 x 50 µl|
|AGC-037||1 x 50 µl|
The transport of Glu into the cells by the EAAT transporters is coupled to the Na+ and K+ electrochemical gradient as a driving force. Hence, the uptake of Glu is dependent on the co-transport of three Na+ and one H+ ions, and the counter transport of one K+ ion.
In addition, to the well documented Glu uptake, the EAAT transporters show a Glu-independent Cl- conductance. The physiological significance of the Cl- current through the EAATs is currently unknown.1,2
Three vesicular glutamate transporters (VGLUTs) have been cloned: BNPI/VGLUT1 (a brain-specific sodium dependent inorganic phosphate (Pi) transporter), and its homologs DNPI/VGLUT2 (differentiation-associated sodium-dependent Pi transporter) and VGLUT33. These transporters mediate glutamate uptake inside presynaptic vesicles and are anatomical and functional markers of glutamatergic excitatory transmission4.