Alomone Labs is pleased to offer the Histamine Receptor Antibody Explorer Kit (#AK-560). The Explorer Kit contains histamine receptor antibodies, ideal for screening purposes.
|Product Name||Cat #||Size|
|AHR-001||1 x 50 µl|
|AHR-002||1 x 50 µl|
|AHR-003||1 x 50 µl|
|AHR-004||1 x 50 µl|
Histamine (2-[4-imidazole]ethylamine) is a low-molecular-weight amine synthesized from L-histidine. It is produced by various cells throughout the body, including central nervous system neurons, gastric mucosa parietal cells, mast cells, basophils and lymphocytes. Histamine is a major biological mediator whose functions include, among many others, regulation of vascular smooth muscle, immune regulation, regulation of sleep-wake cycles and regulation of gastric acid secretion.1
The biological effects of histamine are mediated through four receptors (H1- H4 Histamine receptors) all of which belong to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily.
- Hill, S.J. (1997) Pharmacol. Rev. 49, 253.