Name: Melanocortin Receptor Antibody Explorer Kit
Brand: Alomone Labs
SKU: AK-565

Overview

Cat #: AK-565

Size: 10 Vials

Form: Lyophilized

Alomone Labs is pleased to offer the Melanocortin Receptor Antibody Explorer Kit (#AK-565). The Explorer Kit contains melanocortin receptor antibodies, ideal for screening purposes.

For research purposes only, not for human use

Compounds

Product Name	Cat #	Size
Anti-MC1 Receptor Antibody	AMR-020	1 x 50 µl
MC1 Receptor Blocking Peptide	BLP-MR020	1 x 40 µg
Anti-MC2 Receptor (extracellular) Antibody	AMR-022	1 x 50 µl
MC2 Receptor (extracellular) Blocking Peptide	BLP-MR022	1 x 40 µg
Anti-MC3 Receptor (extracellular) Antibody	AMR-023	1 x 50 µl
MC3 Receptor (extracellular) Blocking Peptide	BLP-MR023	1 x 40 µg
Anti-MC4 Receptor (extracellular) Antibody	AMR-024	1 x 50 µl
MC4 Receptor (extracellular) Blocking Peptide	BLP-MR024	1 x 40 µg
Anti-MC5 Receptor Antibody	AMR-025	1 x 50 µl
MC5 Receptor Blocking Peptide	BLP-MR025	1 x 40 µg

Scientific Background

Scientific Background The melanocortin signaling system plays a role in many physiological outcomes such as skin pigmentation, food intake, sexual behavior and more. Melanocortin receptors (MCRs) 1 through 5, belong to the superfamily of G-protein coupled receptors, and mediate the effects of five different peptides: ACTH, α-MSH, β-MSH and γ-MSH. In addition, this system has endogenous antagonists: agouti and AGRP. Agouti inhibits MCR1 and MCR4, while AGRP antagonizes MCR3 and MCR4. These two antagonists, when overexpressed in mice, give rise to obese animals, and in some cases, obese and diabetic subjects.¹

References

Gantz, I. and Fong, T.M. (2003) Am. J. Physiol. 284, E468.

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Shipping and Ordering information

Order Summary

Melanocortin Receptor Antibody Explorer Kit

Overview

Compounds

Anti-MC1 Receptor Antibody

MC1 Receptor Blocking Peptide

Anti-MC2 Receptor (extracellular) Antibody

MC2 Receptor (extracellular) Blocking Peptide

Anti-MC3 Receptor (extracellular) Antibody

MC3 Receptor (extracellular) Blocking Peptide

Anti-MC4 Receptor (extracellular) Antibody

MC4 Receptor (extracellular) Blocking Peptide

Anti-MC5 Receptor Antibody

MC5 Receptor Blocking Peptide

Scientific Background

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