Overview
Cat #: AK-103
Size: 18 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the mGluR Antibody Explorer Kit (#AK-103). This Explorer Kit includes antibodies targeted against Glutamate receptors along with their respective peptide control antigen. An ideal tool for screening purposes.
For research purposes only, not for human use
Compounds
Scientific Background
Scientific Background Metabotropic glutamate receptors (mGluRs) belong to the super family of G-protein coupled receptors (seven transmembrane proteins). mGluRs are further divided into subfamilies: group I mGluRs (mGluR1 and mGluR5) which couple to Gq, thereby activating phospholipase C (PLC). Group II which include mGluR2 and mGluR3 couple to Gi, therefore inhibit the formation of adenylate cyclase. mGluR4, 6, 7, 8 which belong to group III also inhibit adenylate cyclase formation by coupling to Gi.
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