This product has recently been released.
This product is freeze dried. All water molecules have been removed.
The activity of this product has been verified and approved by our professional team.
Centrifuge all products before handling (10000 x g 5 min).
It is recommended to aliquot stock solutions to prevent repeated thawing and freezing.
ML-301 is a fully selective imidazole-based agonist of neurotensin receptor 1 (NTR1). It stimulates NTR1-mediated calcium mobilization with an EC50 value of 289 nM1. The carboxylic acid moiety increases the compound’s solubility1.
To date, four neurotensin receptors have been cloned from human: NTR1, NTR2, NTR3 and NTR4 which belong to the super family of G-protein coupled receptors (GPCRs). NTR1 mediates most of the known neurotensin ligand effects and is a potential therapeutic target2.
ML-301 (#M-315) is a highly pure, synthetic, and biologically active compound.