Neuroligin & Neurexin Antibody Explorer Kit

A Screening Package of Neuroligin & Neurexin Antibodies Economically Priced
  • Lyophilized Powder
  • Antigen Incl.
Cat #: AK-595
Last update: 24/01/2020

Neuroligin & Neurexin Antibody Explorer Kit (#AK-595) contains specific Nlgn and Nrxn antibodies. Ideal for screening purposes.

For research purposes only, not for human use

Compounds

Scientific Background

Scientific Background
    • Neurexins (NRXNs) are a family of transmembrane, synaptic adhesion molecules. They are largely presynaptic proteins that form a trans-synaptic cell-adhesion complex with postsynaptic neuroligins1. They are encoded by three genes (NRXN1, NRXN2 and NRXN3), each giving rise to various isoforms. The α-isoforms and β-isoforms of each neurexin are single-pass transmembrane proteins maintaining identical transmembrane and intracellular domains but having distinct extracellular domains1.

      Neuroligins (NLGNs) are a family of postsynaptic cell adhesion molecules that play an important role in synaptic development and function2. Four genes encode for the different members of the neuroligin family in mammals: NLGN 1-4, which are differentially enriched in postsynaptic specializations of synapses3.

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