Overview
Cat #:
Size:
1 g
Lot:
T170SM011
Alternative Name Micardis, Kinzalmono, Pritor
Lyophilized Powder yes
Source Synthetic
MW: 514.6
Purity: ≥99%.
Effective concentration 1-500 nM.
Structure
Chemical name 2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid.
Molecular formula C33H30N4O2.
CAS No.: 144701-48-4
PubChem CID 65999
Activity An antagonist of Angiotensin II type-1 receptor1.
References-Activity
- Kumar, A.S. et al. (2010) Beilstein. J. Org. Chem. 6, 25.
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility 25 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
- Alomone Labs Telmisartan inhibits the activation of AT1R expressed in CHO-K1-mt aequorin-Gα16 cells.Dose response curve for the inhibition of AT1R expressed in CHO-K1-mt aequorin-Gα16 cells. Ca2+ response, as detected by elevation in aequorin derived fluorescence following 0.04 nM Angiotensin II application, was inhibited by increasing concentrations of Telmisartan (T-170). 500 nM Telmisartan fully inhibited the activation by Angiotensin II.
Target AT1R receptors
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
Citations