TRPV1 (also named VR1, capsaicin receptor and vanilloid receptor) is a member of the transient receptor potential (TRP) channel family, which includes TRPC, TRPM, TRPA, TRPP, TRPML and the TRPV subfamilies. The TRPV subfamily consists of six members named, TRPV1-6. The TRPV1 channel is a vanilloid-gated, nonselective cation channel.

TRPV1 has many activators among them heat, protons, vanilloids like Capsaicin, Resiniferatoxin (RTX), and lipids. This channel is associated with tissue injury and inflammation^1,2.