Free shipping starts now, no minimum, no coupons required!

Voltage-Gated Na+ Channels

Activators

Voltage-gated Na­­­­­­­+ (NaV) channels are important for the generation and propagation of signals in electrically excitable tissues like the muscle, heart, and nerve. Activation of these channels ultimately leads to muscular contraction, cardiac rhythm, and neuronal firing. Nine mammalian isoforms of voltage-gated Na­­­­­­­+ channels have been identified (NaV1.1-NaV1.9). Nine genes (SCN1A, SCN2A, etc.) encoding distinct α subunit isoforms and 4 β subunit genes (SCN1B, SCN2B, etc.) have been identified in the human genome. The nine isoforms share a similar (but complex) architecture.

Displaying 1 to 20 (out of 29 products)
  • Cn2 Toxin

    An activator of Nav1.6
    Cat # STC-060
    Source Synthetic
    MW 7589 Da
    Target Nav1.6 channels
    • Bioassay Tested
  • Heteropodatoxin-1

    An inhibitor of Kv4.2 and Nav1.7 and an activator of Nav1.9.
    Cat # STH-320
    Source Synthetic
    MW 3910.4 Da
    Target Nav1.9, Nav1.7 and Kv4.2
    • Bioassay Tested
  • Hj1a Toxin

    An Activator of NaV1.1 Channel
    Cat # STH-450
    MW 7482.4 Da
    Target Nav1.1 channels
    • Bioassay Tested
  • Iota-Conotoxin RXIA

    An Activator of NaV1.6, NaV1.2 and NaV1.7 Channels
    Cat # STI-300
    MW 4975 Da.
    Target Nav1.6, Nav1.2 and Nav1.7 channels
    • Bioassay Tested
  • 1Kα-Pompilidotoxin

    An Activator of NaV Channels

    Cat # P-172
    MW 1502 Da.
    Target NaV Na+ channels
    • Bioassay Tested
  • 1Kβ-Pompilidotoxin

    An Activator of NaV Channels

    Cat # P-182
    MW 1531 Da.
    Target NaV Na+ channels
    • Bioassay Tested
  • 3Rα-Pompilidotoxin

    An Activator of NaV Channels

    Cat # P-174
    MW 1558 Da.
    Target NaV Na+ channels
    • Bioassay Tested
  • 3R12Rα-Pompilidotoxin

    An Activator of NaV Channels

    Cat # P-176
    MW 1586 Da.
    Target NaV Na+ channels
    • Bioassay Tested
  • α-Pompilidotoxin

    An Enhancer of NaV Currents

    Cat # P-170
    MW 1529 Da.
    Target TTX-sensitive Nachannels
    • Bioassay Tested
  • β-Pompilidotoxin

    An Enhancer of NaV Currents

    Cat # P-180
    MW 1559 Da.
    Target TTX-sensitive Na+ channels
    • Bioassay Tested
  • AaH1 Toxin

    A Potent NaV Channel Inhibitor of Inactivation

    Cat # STA-155
    MW 6804 Da.
    Target NaV channels
    • Bioassay Tested
  • Aconitine

    An Activator of NaV Channels

    Cat # A-150
    Source Natural
    MW 645.74
    Target NaV Na+ channels
    • Bioassay Tested
  • Anthopleurin-C

    A Potent Activator of NaV Channels

    Cat # A-400
    MW 4884 Da.
    Target NaV channels
    • Bioassay Tested
  • ATX-II

    A Modulator of NaV Channels

    Cat # STA-700
    MW 4935 Da.
    Target Various NaV channels
    • Bioassay Tested
  • BDS-I

    A Blocker of KV3 Channels and a Modulator of NaV Channels

    Cat # STB-400
    MW 4708 Da.
    Target KV3 K+ channels, NaV Na+ channels
    • Bioassay Tested
  • BmKI Toxin

    An Activator of NaV Channels

    Cat # STB-100
    MW 7217 Da.
    Target NaV1.4, NaV1.5, NaV1.6
    • Bioassay Tested
  • Hm1a Toxin

    A Selective and Potent Activator of NaV1.1 Channels and Blocker of KV2 and KV4 Channels

    Cat # STH-601
    MW 3996.4 Da.
    Target NaV1.1, KV2, KV4 channels
    • Bioassay Tested
  • Jingzhaotoxin-II

    An Activator of NaV Channels

    Cat # STJ-150
    MW 3561 Da.
    Target NaV Na+ Channels
    • Bioassay Tested
  • NaV1.1-Compound 3a

    A Modulator of NaV1.1 Channel

    Cat # CMN-002
    Source Synthetic
    MW 344.41
    Target NaV1.1 channels
    • Bioassay Tested
  • Tf2 Toxin

    An Opener of NaV1.3 and NaV1.9 Channels

    Cat # STT-050
    MW 6954 Da.
    Target NaV1.3, NaV1.9 channels
    • Bioassay Tested

* See product page

Displaying 1 to 20 (out of 29 products)