Agonists

Purinergic (P2X) Receptors

Agonists

The P2X receptors belong to the ligand-gated ion channel family and are activated by extracellular ATP. The structure and function of the P2X receptors, investigated mainly using in vitro models, indicate their involvement in synaptic communication, cell death, and differentiation. Seven mammalian P2X receptor subtypes (P2X1–P2X7) have been identified and cloned. All P2X receptor subtypes share the same structure of intracellular N and C-termini two membrane-spanning domains and a large extracellular loop.

Displaying 1 to 4 products (out of 4 products)
  • BomoTx

    A Somatosensory, Pain Inducing Neuron Stimulator, Indirect P2X2/P2X3 Receptor Agonist

    Cat # NTB-200
    Source Natural
    MW 13,834 Da.
    Target P2X2/P2X3 receptors
    • Lyophilized Powder
  • BzATP triethylammonium salt

    An Agonist of P2X7 Receptors

    Cat # A-385
    Source Synthetic
    MW 1018.97
    Target P2X7 receptors
  • Garcinolic acid

    A Positive Modulator of P2X7 Receptors

    Cat # G-155
    Source Natural
    MW 646.78
    Target P2X7 receptors
  • Ivermectin

    A Positive Allosteric Modulator of α7 nAChR and of human P2X4 Receptor

    Cat # I-110
    Source Synthetic
    MW 875.09
    Target α7 nAChR, P2X, GABA(A)R

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Displaying 1 to 4 products (out of 4 products)