5-Hydroxytryptamine Receptors (Serotonin Receptors)


Serotonin (5-hydroxytryptamine, 5-HT) plays unequivocally a most important role in the normal physiology amongst higher eukaryotes, as do most neurotransmitters. To date, some fifteen serotonin receptors have been cloned and grouped into seven families (5-HT1-5-HT7) based on their signaling mechanisms. The 5-HT1 receptor class comprises 5 different receptors with ranging homology. Apart from 5-HT3, all serotonin receptors belong to the G-Protein Coupled Receptor superfamily and therefore span the membrane seven times.

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  • Mirtazapine

    An Antagonist of 5-HT2, 5-HT3, Histamine H1 Receptors and α2-Adrenoceptor

    Cat # M-130
    Source Synthetic
    MW 265.4
    Target 5-HT3, 5-HT2, Histamine H1, α2 adrenergic receptors
    • Lyophilized Powder

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