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Formyl Peptide Receptors


Chemotactic factors from both Gram-positive and Gram-negative bacteria are short peptides with N-formyl methionine at the N-terminus. These peptides are released from bacteria during infection and activate formyl peptide receptor (FPR), a member of G-protein coupled receptors (GPCRs). In human, the FPR family consists mainly of three receptors, FPR1, FPR2/ALX (formerly FPRL1), and FPR3 (formerly FPRL2) which all couple to the Gi subtype of G-proteins and ultimately lead to the activation of phospholipase C and intracellular Ca2+ increase.

Displaying 1 to 2 products (out of 2 products)
  • Quin-C7

    An Antagonist of FPR2 Receptor

    Cat # Q-155
    Source Synthetic
    MW 431.49
    Target FPR2 receptors
    • Bioassay Tested
  • WRW4

    A Potent Antagonist of FPR2 and FPR3 G-Protein Coupled Receptors

    Cat # GPW-110
    MW 1104.3 Da
    • Bioassay Tested

* See product page

Displaying 1 to 2 products (out of 2 products)