Antibodies

Cyclic Nucleotide-Gated Cation Channels

Antibodies

Cyclic nucleotide-gated channels (CNGs) were first discovered by the observation that cGMP directly activates a current in retinal rods. Soon after, the first CNG channel was cloned. cAMP and cGMP, both activators of CNG channels do so by binding to a specific site on the channels. Indeed, it takes more than one molecule (probably 4) to fully open the tetrameric channel. Mammalian cells express six different isoforms of cyclic nucleotide-gated cation channels which fall into two separate subfamilies: the first, CNGA1-4 represents the principal subunits, those able to form functional channels (except for CNGA4). The second subfamily includes two subunits, namely, CNGB1 and CNGB3. These proteins act as auxiliary subunits and thus cannot form channel-like structures on their own.

Displaying 1 to 5 products (out of 5 products)
  • Anti-CNGA1 Antibody

    A Rabbit Polyclonal Antibody to CNGA1 Channel

    Cat # APC-071
    Type Polyclonal
    Source Rabbit
    Applications wb, ic*, ifc*, ih*, ip*
    Reactivity r, h*, m*
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Anti-CNGA2 Antibody

    A Rabbit Polyclonal Antibody to CNGA2 Channel

    Cat # APC-045
    Type Polyclonal
    Source Rabbit
    Applications ic, ih, wb, ifc*, ip*
    Reactivity h, m, r
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Anti-CNGA3 Antibody

    A Rabbit Polyclonal Antibody to CNGA3 Channel

    Cat # APC-060
    Type Polyclonal
    Source Rabbit
    Applications ih, wb, ic*, ifc*, ip*
    Reactivity m, r
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Anti-CNGA4 Antibody

    A Rabbit Polyclonal Antibody to CNGA4 Channel

    Cat # APC-074
    Type Polyclonal
    Source Rabbit
    Applications ih, wb, ic*, ifc*, ip*
    Reactivity m, r, h*
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • CNGA Antibody Explorer Kit

    A Screening Package of CNGA Antibodies Economically Priced

    Cat # AK-204
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.

* See product page

Displaying 1 to 5 products (out of 5 products)