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Guinea Pig-Raised Polyclonal Antibodies

 

Flexibility. Specificity. Satisfaction.

 

Antibodies raised in guinea pig can be used with antibodies raised in mouse, rabbit, goat, etc. in complex immunostaining or immunoprecipitation protocols.

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Metabotropic Glutamate Receptors

Antibodies to mGluRs

Metabotropic glutamate receptors (mGluRs) belong to the super family of G-protein coupled receptors (seven transmembrane proteins). mGluRs are further divided into subfamilies: group I mGluRs (mGluR1 and mGluR5) which couple to Gq, thereby activating phospholipase C (PLC). Group II which include mGluR2 and mGluR3 couple to Gi, therefore inhibit the formation of adenylate cyclase. mGluR4, 6, 7, 8 which belong to group III also inhibit adenylate cyclase formation by coupling to Gi.

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