ATTO-Conjugated Antibodies

Sphingosine 1-Phosphate Receptors

ATTO-Conjugated Antibodies

Sphingosine 1-phosphate (S1P) is an active byproduct of sphingomyelin metabolism. Upon secretion, it circulates in the blood via its binding to high-density lipoproteins and albumin. When S1P reaches its target cell it could activate 5 different high affinity receptors belonging to the G-protein coupled receptor superfamily: Sphingosine 1-phosphate receptors, termed S1PR1-5. Stimulation of S1PR receptors triggers a cascade of signaling events depending on the receptor and on the G-protein it couples. Through the different signaling pathways these receptors activate, S1PR receptors are implicated in adherens junction assembly, cytoskeletal changes, cell migration, proliferation and apoptosis.

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  • Anti-S1PR3 (EDG3) (extracellular)-ATTO-488 Antibody

    A Rabbit Polyclonal Antibody to Sphingosine 1-Phosphate Receptor 3 Conjugated to the Fluorescent Dye ATTO-488

    Cat # ASR-013-AG
    Type Polyclonal
    Host Rabbit
    Applications fc, ic*, ih*, lci*
    Reactivity h, m, r
    • Lyophilized Powder
    • Antigen Incl.

* See product page

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