Biotinylated Toxins

GABA(A) Receptors

Biotinylated Toxins

GABA(A) Receptors are ionototropic γ-aminobutyric acid type A receptors. Most of the fast inhibitory synaptic transmissions in the brain are mediated by these ligand-gated ion channels in response in to γ-aminobutyric binding. To date 19 GABA(A) Receptors have been cloned in the mammalian central nervous system (CNS) and are classified by their sequence identity into 7 different subunits (α, β, γ, δ, ε, π, and θ). They consist of pentameric structures assembled by different subunits which are mainly permeable to Cl-that act to reduce neuronal excitation. Alomone Labs is pleased to offer peptide toxins which affect a variety of GABA(A) receptors, conjugated to biotin.

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  • α-Bungarotoxin-Biotin

    A Biotinylated Conjugate for Sensitive Detection of Neuromuscular Junctions, GABA(A) Receptors, nAChRs, and α-Bungarotoxin Binding Sites

    Cat # B-100-B
    Source Modified natural protein
    MW ~9030 Da.
    Target α7, α1/β1/γ/δ nAChR, GABA(A) receptor subtypes

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