Blockers

Acid-Sensing Ion Channels (ASIC)

Blockers

ASIC channels belong to the ENaC/Degenerin superfamily and are proton-gated ion channels which are not voltage-dependent. Six different genes encode the different ASIC subunits and splice variants: ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3 and ASIC4. The topology of ASIC channels is predicted on the basis of that of ENaCs. However, different computational programs have depicted different structures for the ASICs.

Displaying 1 to 15 products (out of 15 products)
  • Amiloride hydrochloride

    Blocker of ENaC/ASIC/Degenerin Channels

    Cat # A-140
    Source Synthetic
    MW 266.09
    Target ENaC, ASIC, TRPP3 channels, NHE-1 transporter
    • Lyophilized Powder
  • APETx2

    A Blocker of ASIC3 Channel

    Cat # STA-160
    Source Synthetic
    MW 4561 Da.
    Target ASIC3 channels
    • Lyophilized Powder
  • Benzamil

    An Inhibitor of Na+/Ca2+ Exchangers and a Blocker of ASIC, TRPP3 and TRPA1 Channels

    Cat # B-161
    Source Synthetic
    MW 319.75
    Target Na+/Ca2+ exchangers, ASIC/ENaC, TRPP3, TRPA1 channels
    • Lyophilized Powder
  • Benzamil hydrochloride

    An Inhibitor of Na+/Ca2+ Exchangers and a Blocker of ASIC, TRPP3 and TRPA1 Channels

    Cat # B-160
    Source Synthetic
    MW 356.21
    Target Na+/Ca2+ exchangers, ASIC/ENaC, TRPP3, TRPA1 channels
    • Lyophilized Powder
  • Hm3a Toxin

    A Highly Potent ASIC1a Blocker and ASIC1b Activator

    Cat # STH-250
    Source Synthetic peptide
    MW 4287.1 Da.
    Target ASIC1a and ASIC1b
    • Lyophilized Powder
  • HMA

    An Antagonist of Na+/H+ Exchangers, P2X7 receptors and TRPA1, ASIC3 Channels

    Cat # H-130
    Source Synthetic
    MW 311.77
    Target NHE exchangers, TRPA1, ASIC3 channels, P2X7 receptors
    • Lyophilized Powder
  • Mambalgin-1

    A Selective and Reversible ASIC1a Blocker

    Cat # STM-100
    Source Synthetic Peptide
    MW 6554.5 Da.
    Target ASIC1 channels
    • Lyophilized Powder
  • Mambalgin-3

    A Blocker of ASIC1a and ASIC1b Channels

    Cat # M-300
    Source Natural protein
    MW 6566 Da.
    Target ASIC1 channels
    • Lyophilized Powder
  • Psalmotoxin-1

    A Potent Blocker of ASIC1a Channels

    Cat # STP-200
    Source Synthetic peptide
    MW 4689.5 Da.
    Target ASIC1a channels
    • Lyophilized Powder
  • ASIC Channel Modulator Explorer Kit

    A Screening Package of ASIC Channel Modulators Economically Priced

    Cat # EK-113
    • Lyophilized Powder
  • Classical Ion Channel Blockers for Pain Research Explorer Kit

    A Screening Package of Classical Ion Channel Blockers for Pain Research Economically Priced

    Cat # EK-355
    • Lyophilized Powder
  • ASIC1 Channel Basic Research Pack

    All You Need for ASIC1 Channel Research

    Cat # ESB-200
    • Lyophilized Powder
    • Antigen Incl.
  • ASIC1 Channel Premium Research Pack

    All You Need for ASIC1 Channel Research

    Cat # ESP-200
    • Lyophilized Powder
    • Antigen Incl.
  • ASIC3 Channel Basic Research Pack

    All You Need for ASIC3 Channel Research

    Cat # ESB-201
    • Lyophilized Powder
    • Antigen Incl.
  • ASIC3 Channel Premium Research Pack

    All You Need for ASIC3 Channel Research

    Cat # ESP-201
    • Lyophilized Powder
    • Antigen Incl.

* See product page

Displaying 1 to 15 products (out of 15 products)