Ion Channels in Epilepsy

• Kynurenic acid

  An Antagonist of Ionotropic Glutamate Receptors and α7 nAChR

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  Cat # K-110

  Source Synthetic

  MW 189.2

  Target iGluR, α7 nAChR

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• L-689,560

  A Potent and Selective Antagonist of NMDA Receptors

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  Cat # L-225

  Source Synthetic

  MW 380.23

  Target NMDA receptors

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• Linopirdine

  A Blocker of KCNQ (K_V7) Channels

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  Cat # L-155

  Source Synthetic

  MW 391.46

  Target KCNQ K⁺ channels

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  • 

• Linopirdine dihydrochloride

  A Blocker of KCNQ (K_V7) Channels

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  Cat # L-156

  Source Synthetic

  MW 464.39

  Target KCNQ K⁺ channels

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• Maurotoxin

  A Potent Blocker of K_Ca and K_V1 K⁺ Channels

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  Cat # STM-340

  MW 3612 Da

  Target K_Ca and K_V1 K⁺ channels

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• MCD peptide

  A Potent and Selective Blocker of K_V1.1 and K_V1.2 Channels

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  Cat # STM-250

  MW 2588 Da

  Target K_V1.1, K_V1.2 K⁺ channels

  More info

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• Mibefradil dihydrochloride hydrate

  A Blocker of T-type Ca_V, Orai1-3, and K_V10.1 Channels

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  Cat # M-150

  Source Synthetic

  MW 568.55

  Target Ca_V3, Orai1-3, K_V10.1 channels

  More info

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• (+)-MK 801 maleate

  An Antagonist of NMDA Receptors

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  Cat # M-230

  Source Synthetic

  MW 337.4

  Target NMDA receptors

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• ML 218

  A Selective Blocker of T-type Channels

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  Cat # M-165

  Source Synthetic

  MW 369.3

  Target T-type Ca_V channels

  More info

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• ML 218 hydrochloride

  A Selective Blocker of T-type Channels

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  Cat # M-166

  Source Synthetic

  MW 405.8

  Target T-type Ca_V channels

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• MmTx1 Toxin

  A Super Potent Allosteric Modulator of GABA(A) Receptors

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  Cat # STM-550

  MW 7205 Da

  Target GABA(A) receptors

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• MPX-004

  A Potent and Selective Antagonist of GluN2A-containing NMDA Receptors

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  Cat # M-280

  Source Synthetic

  MW 455.91

  Target GluN2A-containing NMDA receptors

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  • 

• N-Me-aminopyrimidinone 9

  A Specific Blocker of Na_V1.7 Channel

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  Cat # N-310

  Source Synthetic

  MW 303.4

  Target Na_V1.7 channels

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• Na_V1.7-Compound 36

  A Potent and Selective Blocker of Na_V1.7 Channels

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  Cat # CMN-003

  Source Synthetic.

  MW 486.85

  Target Na_V1.7 channels

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• NNC 55-0396 dihydrochloride

  A Blocker of T-type Ca_V Channels

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  Cat # N-205

  Source Synthetic

  MW 564.57

  Target T-type Ca_V channels

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  • 

• NNC 55-0396 dihydrochloride hydrate

  A Blocker of T-type Ca_V Channels

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  Cat # N-206

  Source Synthetic

  MW 573.48

  Target T-type Ca_V channels

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  • 

• Noxiustoxin

  A Potent Blocker of K_V1.2 and K_V1.3 Channels

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  Cat # STN-340

  MW 4194 Da

  Target K_V1.2, K_V1.3 K⁺ channels

  More info

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• NS8593

  A Blocker of K_Ca2 and TRPM7 Channels

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  Cat # N-196

  Source Synthetic

  MW 263.3

  Target SK K⁺ channels, TRPM7

  More info

  • 

• NS8593 hydrochloride

  A Blocker of K_Ca2 and TRPM7 Channels

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  Cat # N-195

  Source Synthetic

  MW 299.79

  Target SK K⁺ channels, TRPM7

  More info

  • 

• Oroxylin A

  An Antagonist of GABA(A) Receptors

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  Cat # O-160

  Source Natural

  MW 284.26

  Target GABA(A) receptors

  More info

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