Blockers

Lysosomal Ion Channels

Blockers

Lysosomes are intracellular acidic organelles containing over 60 different types of hydrolases. They are responsible for the degradation of intracellular components from autophagy and of extracellular particles from endocytosis. Lysosomes contain a large number of membrane proteins, some of them being ion channels which play an important role in regulating membrane potential and lysosomal ionic homeostasis. Thus far the following native ionic conductances have been revealed in single channel recordings and in whole-lysosomal recordings from artificially enlarged lysosomes: K+, Na+, Cl, Ca2+ and H+.

Displaying 1 to 2 products (out of 2 products)
  • Chlorotoxin

    An Inhibitor of Chloride Channels

    Cat # RTC-450
    Source Recombinant, E. coli
    MW 3996 Da.
    Target Chloride channels
  • Chlorotoxin

    An Inhibitor of Chloride Channels

    Cat # STC-460
    Source Synthetic peptide
    MW 3995 Da.
    Target Chloride channels

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Displaying 1 to 2 products (out of 2 products)