Blockers

Voltage-Gated K+ Channels

Blockers

K+ selective channels are some of the most widespread ion trafficking molecules in living organisms, with more than 70 genes encoding different K+ channels in humans. KV channels fall into one of the two classical categories of delayed rectifier (DR) and A-type. Delayed rectifier was the original name attributed to voltage-dependent K+ channels due to their delayed activation in squid giant axons. A-type channels are low voltage-activated, fast inactivating (therefore, transient) K+ channels. Specific KV toxins are often used to dissect the particular contribution of different subunits to native currents.

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Displaying 1 to 20 (out of 96 products)
  • 4-Aminopyridine

    A Non-Specific K+ Channel Blocker

    Cat # A-115
    Source Synthetic
    MW 94.1
    Target KV K+ channels
    • Lyophilized Powder
  • κ-Conotoxin RIIIJ

    Voltage-Gated K+ Channel Blocker

    Cat # STC-660
    MW 2807.9 Da.
    Target KV1.2 K+ channels
    • Lyophilized Powder
  • κ-Conotoxin RIIIK

    A Specific Potent Blocker of KV1.2 K+ Channels

    Cat # STC-650
    MW 2648 Da.
    Target KV1.2 K+ channels
    • Lyophilized Powder
  • Aa1 Toxin

    A Novel Blocker of Shaker-B and IA K+ Channels

    Cat # RTA-400
    MW 3868 Da.
    Target KV1.3 K+ channels
    • Lyophilized Powder
  • Aam-KTX

    A Blocker of Voltage-Gated K+ channels

    Cat # STA-110
    MW 4185 Da.
    Target KV K+ channels
    • Lyophilized Powder
  • ADWX-1

    A Blocker KV1.3 K+ Channels

    Cat # STW-100
    MW 4072 Da.
    Target KV1.3 K+ channel
    • Lyophilized Powder
  • Agitoxin-1

    A Potent Blocker of KV1.3 Channels

    Cat # RTA-150
    MW 4015 Da.
    Target KV1.3 channels
    • Lyophilized Powder
  • Agitoxin-2

    A Potent Blocker of KV1.3 K+ Channels

    Cat # STA-420
    MW 4091 Da.
    Target KV1.3 K+ channels
    • Lyophilized Powder
  • Agitoxin-2-Cys-TAMRA

    A Novel Marker of KV1.3 K+ Channels

    Cat # RTA-420-T
    MW 4673 Da.
    Target KV1.3 K+ channels
    • Lyophilized Powder
  • Agitoxin-3

    A Potent Blocker of KV1.3 K+ Channels

    Cat # RTA-390
    MW 4101 Da.
    Target KV1.3 K+ channels
    • Lyophilized Powder
  • AmmTx3 Toxin

    A Blocker of A-Type K+ Channels

    Cat # STA-305
    MW 3822 Da.
    Target KV4 K+ channels
    • Lyophilized Powder
  • BDS-I

    A Blocker of KV3 Channels and a Modulator of NaV Channels

    Cat # STB-400
    MW 4708 Da.
    Target KV3 K+ channels, NaV Na+ channels
    • Lyophilized Powder
  • BDS-II

    A Blocker of KV3 Channels and a Modulator of NaV Channels

    Cat # B-450
    MW 4776 Da.
    Target KV3 K+ channels, NaV Na+ channels
    • Lyophilized Powder
  • BeKm-1

    A Novel ERG1 (KV11.1) K+ Channel Blocker

    Cat # STB-470
    MW 4092 Da.
    Target KV11.1 K+ channels
    • Lyophilized Powder
  • Carvedilol

    A Blocker of KV1.5 and Kir2.3 Channels and an Antagonist of Adrenoceptors

    Cat # C-180
    Source Synthetic
    MW 406.47
    Target KV1.5, Kir2.3 K+ channels, adrenoceptors
    • Lyophilized Powder
  • Charybdotoxin

    A Blocker of KV1.2, KV1.3 and KCa1.1 K+ Channels

    Cat # STC-325
    MW 4296 Da.
    Target KCa1.1, KV1.2, KV1.3 K+ channels
    • Lyophilized Powder
  • Citalopram

    A Blocker of KV2 Channels and an Inhibitor of 5HT Uptake

    Cat # C-195
    Source Synthetic
    MW 324.4
    Target KV2 K+ channels
    • Lyophilized Powder
  • Citalopram hydrobromide

    A Blocker of KV2 Channels and an Inhibitor of 5-HT Uptake

    Cat # C-185
    Source Synthetic
    MW 405.31
    Target KV2 K+ channels
    • Lyophilized Powder
  • CP 339818 hydrochloride

    A Blocker of KV1.3 and KV1.4 K+ Channels

    Cat # C-115
    Source Synthetic
    MW 340.9
    Target KV1.3, KV1.4 K+ channels
    • Lyophilized Powder
  • Dapoxetine hydrochloride

    A Blocker of KV4.3 and KV1.5 Channels and an Inhibitor of 5-HT Re-Uptake

    Cat # D-175
    Source Synthetic
    MW 341.8
    Target KV4.3, KV1.5 channels
    • Lyophilized Powder

* See product page

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