Inhibitors

Protein Phosphatases

Inhibitors

One of the most common post-translational modifications is the phosphorylation of proteins at serine, threonine and/or tyrosine residues. Indeed, genetic engineering and mutagenesis studies have also enabled the production of intrinsically activated mutants which biologically “mimic” the phosphorylated form of the protein. Along with protein phosphorylation, the cell needs to be able to reverse the activated/non-activated form of the protein via the removal of the phosphate group. Protein phosphatases play such a role in the cell and are responsible for removing phosphate groups from serine/threonine and tyrosine residues.

Displaying 1 to 12 products (out of 12 products)
  • 1-Norokadaone

    An Inactive Homologue of Okadaic Acid and Okadaol, Inhibitors of Protein Phosphatase 1 and Protein Phosphatase 2A

    Cat # N-750
    Source Synthetic
    MW 758.99
  • Ascomycin

    Immunosuppressant

    Cat # A-800
    Source Natural
    MW 792
  • Calyculin A

    A Potent Inhibitor of Protein Phosphatase 1 and Protein Phosphatase 2

    Cat # C-100
    Source Natural
    MW 1009.2
  • Cantharidic Acid

    A Potent Inhibitor of Protein Phosphatase 1 and Protein Phosphatase 2A

    Cat # C-250
    Source Semi-synthetic
    MW 258.18
  • Cantharidin

    A Potent Inhibitor of Protein Phosphatase 1 and Protein Phosphatase 2A

    Cat # C-170
    Source Natural
    MW 196.2
  • Cyclosporin A

    An Immunosuppressant and an Inhibitor of Protein Phosphatase 2B

    Cat # C-900
    Source Natural
    MW 1202.64
  • Endothall

    An Inhibitor of Protein Phosphatase 1 and Protein Phosphatase 2A

    Cat # E-180
    Source Synthetic
    MW 186.16
  • FK-506

    Calcineurin (PP-2B) Inhibitor-Immunosuppressant

    Cat # F-900
    Source Natural
    MW 804.03
  • Okadaic Acid (ammonium salt)

    A Potent Inhibitor of Protein Phosphatase 1 and Protein Phosphatase 2

    Cat # O-800
    Source Natural
    MW 822.04
  • Okadaic Acid (sodium salt)

    A Potent Inhibitor of Protein Phosphatase 1 and Protein Phosphatase 2A

    Cat # O-900
    Source Natural
    MW 827
  • Okadaol

    An Inhibitor of Protein Phosphatase 1 and Protein Phosphatase 2A

    Cat # O-700
    Source Semi-synthetic
    MW 791.03
  • Rapamycin

    An Immunosuppresant, Anticancer Compound, and Protein Phosphatase Inhibitor

    Cat # R-900
    Source Natural
    MW 914.2

* See product page

Displaying 1 to 12 products (out of 12 products)