Intracellular Ca<sup>2+</sup> Modulators

Ca2+ Signaling

Intracellular Ca2+ Modulators

Ca2+ can influence various cellular outcomes by either entering the cell from the extracellular milieu or by being released from intracellular stores, such as the endoplasmic reticulum (ER). Ca2+ release from the ER is influenced by a number of factors like the activation of G-protein coupled receptors and receptor tyrosine kinases which activate downstream pathways leading to Ca2+ release. There are also membrane proteins located on the ER membrane which are known to influence Ca2+ release. Such proteins include IP3R, ryanodine receptors (RyRs) and various pumps. Many compounds can either promote or inhibit Ca2+ release from the ER. Alomone Labs is pleased to offer various small molecules and peptides known to modulate Ca2+ release from intracellular stores.

Displaying 1 to 16 products (out of 16 products)
  • A23187

    Widely used Ca2+ Ionophore

    Cat # A-600
    Source Natural
    MW 523.6
  • Anhydroryanodine

    A Non Active Analogue of Ryanodine

    Cat # A-510
    Source Natural
    MW 475.54
    • Lyophilized Powder
  • Chelerythrine chloride

    An Inhibitor of Protein Kinase C, SERCA Pump, and P2X7 Receptor

    Cat # C-400
    Source Natural
    MW 383.84
    Target PKC, SERCA pumps, P2X7 receptor
  • Cyclopiazonic Acid

    A Potent Inhibitor of Intracellular Ca2+-ATPase Pump

    Cat # C-750
    Source Natural
    MW 336.4
    Target SERCA pump
  • Imperatoxin A

    A Ryanodine Receptor Modulator

    Cat # I-300
    Source Synthetic peptide
    MW 3758 Da.
    Target Ryanodine receptors
  • Ionomycin calcium salt

    A Potent and Selective Ca2+ Ionophore

    Cat # I-700
    Source Natural
    MW 747.08
  • Maurocalcine

    A Ryanodine Receptor 1 and 2 Modulator

    Cat # RTM-100
    Source Recombinant, E. coli
    MW 3864 Da.
    Target Ryanodine receptors
  • NS-1619

    Selective and Potent Enhancer of KCa1.1 Channels and an Inhibitor of SERCA Pumps

    Cat # N-105
    Source Synthetic
    MW 362.2
    Target KCa1.1 K+ channels, SERCA pumps
  • Ochratoxin A

    A Potent Modulator of Ca2+ ATPase Pump

    Cat # O-400
    Source Natural
    MW 403.8
    Target SERCA pump
  • Paxilline

    A Mycotoxin Blocker of KCa1.1 (BK) Channels and SERCA Pumps

    Cat # P-450
    Source Natural
    MW 435.6
    Target KCa K+ channels, SERCA pump
  • Ryanodine

    A Blocker of Ryanodine Receptors

    Cat # R-500
    Source Natural
    MW 493.5
    Target Ryanodine receptors
  • tBuBHQ

    A Potent Inhibitor of Sarcolasmic Reticulum Ca2+ ATPase

    Cat # T-220
    Source Synthetic
    MW 222.33
    Target SERCA
  • Thapsigargin

    A Potent and Cell-Permeable Inhibitor of SERCA Pump Ca2+-ATPase/an Intracellular Ca2+ Mobilizer

    Cat # T-650
    Source Natural
    MW 650.7
    Target SERCA
  • Thapsigargin Epoxide

    A Nonactive Analogue of Thapsigargin

    Cat # T-670
    Source Natural
    MW 632.75
    Target SERCA
  • Cardiac Channel Blocker Explorer Kit

    A Screening Package of Cardiac Channel Blockers Economically Priced

    Cat # EK-345
    • Lyophilized Powder
    • Bioassay Tested
    • Shipped at Room Temp.
    • 100% Net Peptide
  • SERCA Pump Inhibitor Explorer Kit

    A Screening Package of SERCA Pump Inhibitors Economically Priced

    Cat # EK-365
    • Lyophilized Powder
    • Bioassay Tested
    • Shipped at Room Temp.

* See product page

Displaying 1 to 16 products (out of 16 products)